OFFER
Manufacturing plant for production of Solid Forms of Medicinal Products
Pharmacy, Cosmetic Chemistry and Biotechnology Research Group
State-of-the-art technological facilities (modernisation in 2019) ensure the highest manufacturing standards in line with EMA and FDA guidelines. The technology park enables the manufacture of solid forms of investigational medicinal products for clinical trials, including:
→ Short series for rare, orphan diseases
→ Standard series for common diseases
→ Formulations for bioequivalence studies
→ Formulations for preclinical studies
Research topics
→ Permanent forms:
→ Tablets, film-coated tablets, minitablets, granules (immediate-release and modified-release formulations, orally disintegrating tablets)
→ Hard capsules
→ Liquid and semi-liquid forms
→ Ointments, creams and gels,
→ Eye drops
Technological facilities
→ Pharmatech batch mixer (batch size 10 to 50 kg)
→ High-speed granulator (input up to 10 l)
→ Fluidised bed dryer (pelletising up to 0.5 kg, drying up to 0.7 kg)
→ Shelf dryers (loading up to 5 kg/series)
→ Rotary tableting machine, EU-B and EU-D standards (capacity from 600 to 60 000 units/hour)
→ FlexaLab automatic capsule machine, formats 0, 1, 2 and 3
∗ dosing of powders
∗ dosage of mini-pills
∗ dosage of powders and mini-pills
→ Coater with an input of up to 0.5 kg
→ Coater with an input of 2 to 10 kg
→ Blistering machine – aluminium and polymer films
Control and measuring equipment
→ weight-dryer,
→ apparatus for testing hardness, diameter and thickness of tablets,
→ tablet disintegration time apparatus,
→ tablet abrasion testing apparatus,
→ bulk density test apparatus,
→ apparatus for testing mixture parameters (angle of repose, fluidity),
→ microscope equipped with a transmitted and reflected light camera.
